Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomic clustering of tRNA-specific adenosine deaminase ADAT1 and two tRNA synthetases.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 May 2001

Maas S, Kim Y G, Rich A

Abstract excerpt

Human tRNA-specific adenosine deaminase (hADAT1) specifically converts A37 in the anticodon loop of human tRNA(Ala) to inosine via a hydrolytic deamination mechanism. The enzyme is related to a family of RNA editing enzymes (ADARs) specific for pre-mRNA, and it has been cloned based on its sequence homology to the catalytic domain of ADARs. In the present study we have analyzed the 5'-flanking sequence of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Deaminase
Share to Autoimmune Diseases
Share to Chromosomes, Human, Pair 16

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Complementary

Share to Introns

Share to Multigene Family

Share to Radiation Hybrid Mapping

Share to RNA-Binding Proteins

Source

Identifiers

PMID: 11331948
DOI: 10.1007/s003350020008

Genes

ADAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic clustering of tRNA-specific adenosine deaminase ADAT1 and two tRNA synthetases.PMID 11331948Read ↗

The structure of the mouse ADAT2/ADAT3 complex reveals the molecular basis for mammalian tRNA wobble adenosine-to-inosine deamination.Semantic proximity Read ↗

ADAT2/3-mediated tRNA editing promotes cancer cell growth and tumorigenicitySemantic proximity Read ↗

Characterization of the 5′-flanking region of the human RNA-specific adenosine deaminase ADAR1 gene and identification of an interferon-inducible ADAR1 promoterSemantic proximity Read ↗

Biochemical profiling and structural basis of ADAR1-mediated RNA editing.Semantic proximity Read ↗

Structure and sequence determinants required for the RNA editing of ADAR2 substrates.Semantic proximity Read ↗

Origins and evolution of ADAR-mediated RNA editing.Semantic proximity Read ↗

Human RNA-specific adenosine deaminase (ADAR1) gene specifies transcripts that initiate from a constitutively active alternative promoterSemantic proximity Read ↗

RNA editing changes the lesion specificity for the DNA repair enzyme NEIL1.Semantic proximity Read ↗

ANKRD16 prevents neuron loss caused by an editing-defective tRNA synthetase.Semantic proximity Read ↗

An adenosine deaminase that generates inosine at the wobble position of tRNAs.Semantic proximity Read ↗

High-throughput mutagenesis reveals unique structural features of human ADAR1.Semantic proximity Read ↗

Identification and rescue of a tRNA wobble inosine deficiency causing intellectual disability disorder.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.