Article
Association of Short-Term Response to Haloperidol Treatment With a Polymorphism in the Dopamine D<sub>2</sub> Receptor Gene
1 May 2001
Abstract excerpt
OBJECTIVE: Pharmacogenetic influences on therapeutic response to neuroleptic treatment are poorly understood. This study investigates the association of response to short-term haloperidol treatment with a Taq I polymorphism in the DRD2 gene. METHOD: Fifty-seven patients with acute psychosis were treated with haloperidol for up to 28 days. Improvement and response were measured by using the Positive and Negative...
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