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Article

DRD2 genotypic and haplotype variation is associated with improvements in negative symptoms after 6 weeks' amisulpride treatment.

Journal of clinical psychopharmacology - 1 Apr 2015

Kang Seung-Gul, Na Kyoung-Sae, Lee Heon-Jeong, Chee Ik-Seung, Lee Kwanghun, Lee Jonghun

Abstract excerpt

The aim of this study was to identify the association between the rs1079597 and rs1800497 genetic polymorphisms of the gene encoding the dopamine D2 receptor (DRD2) protein and the treatment response to the selective dopamine receptor antagonist amisulpride. After 6 weeks of treatment with amisulpride, 125 schizophrenia patients were interviewed based on the Positive and Negative Syndrome Scale and the Clinical...

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Source

Identifiers

PMID: 25679126
DOI: 10.1097/JCP.0000000000000294

Genes

DRD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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