Article
T102C polymorphism in the 5HT2A gene and schizophrenia: relation to phenotype and drug response variability.
Journal of psychiatry & neuroscience : JPN - 1 Mar 1999
Joober R, Benkelfat C, Brisebois K, Toulouse A, Turecki G, Lal S, Bloom D, Labelle A, Lalonde P, Fortin D, Alda M, Palmour R, Rouleau G A
Abstract excerpt
Although genes play a major role in the etiology of schizophrenia, no major genes involved in this disease have been identified. However, several genes with small effect have been reported, though inconsistently, to increase the risk for schizophrenia. Recently, the 5HT2A 2 allele (T102C polymorphism) was reported to be over-represented in patients with schizophrenia. Other reports have found an excess of allele...
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