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Article

Induction of mutant lymphocytes in cyclophosphamide- and chlorambucil-treated patients.

Mutagenesis - 1 May 2001

Sanderson B J, Johnson K J, Henner W D

Abstract excerpt

Monitoring patients treated with single antineoplastic agents is aiding our understanding of what hazard these drugs pose in vivo. In this study, the frequency of mutant 6-thioguanine-resistant (TG(R)) peripheral blood lymphocytes was monitored before treatment and for < or =35 weeks after treatment of patients with cyclophosphamide (CP) or chlorambucil (CAB). The mean mutant frequency before treatment for six...

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Identifiers

PMID: 11320143
DOI: 10.1093/mutage/16.3.197

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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