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Article

Modulation of HERG current andherg gene expression during retinoic acid treatment of human neuroblastoma cells: Potentiating effects of BDNF

1 Aug 1999

Abstract excerpt

The modulation of herg gene and HERG currents (I(HERG)) was studied in SH-SY5Y neuroblastoma (NB) cells treated with all-trans-retinoic acid (RA) in the absence or presence of the neurotrophin brain-derived neurotrophic factor (BDNF). Both treatments produced a strong increase in the percentage of cells differentiated along the neuronal pathway, with an orientation to a cholinergic phenotype, while a minority of...

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Identifiers

PMID: 10413451
DOI: 10.1002/(sici)1097-4695(199908)40:2<214::aid-neu7>3.0.co;2-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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