Article
Homo-oligomerisation and nuclear localisation of mouse histone deacetylase 1.
Journal of molecular biology - 20 Apr 2001
Taplick J, Kurtev V, Kroboth K, Posch M, Lechner T, Seiser C
Abstract excerpt
Reversible histone acetylation changes the chromatin structure and can modulate gene transcription. Mammalian histone deacetylase 1 (HDAC1) is a nuclear protein that belongs to a growing family of evolutionarily conserved enzymes catalysing the removal of acetyl residues from core histones and other proteins. Previously, we have identified murine HDAC1 as a growth factor-inducible protein in murine T-cells. Here,...
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