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Article

Functional Interaction between Class II Histone Deacetylases and ICP0 of Herpes Simplex Virus Type 1

11 Jun 2004

Abstract excerpt

This study describes the physical and functional interactions between ICP0 of herpes simplex virus type 1 and class II histone deacetylases (HDACs) 4, 5, and 7. Class II HDACs are mainly known for their participation in the control of cell differentiation through the regulation of the activity of the transcription factor MEF2 (myocyte enhancer factor 2), implicated in muscle development and neuronal survival....

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PMID: 15194749
DOI: 10.1128/jvi.78.13.6744-6757.2004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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