Article
Mutations in the p53 tumor suppressor gene in colorectal cancer in Taiwan.
The Kaohsiung journal of medical sciences - 1 Apr 2003
Chang Fu-Hsin, Tzeng Dong-Sheng, Lee Tai-Min, Chen Twu-Chiang, Hsu Li-Sung, Lung For-Wey
Abstract excerpt
Mutations in the tumor suppressor gene p53 have been reported as occurring prevalently in a wide range of human tumors. Detection of a mutated p53 is thought to provide useful information for the clinical management of colorectal neoplasm. In this study, we used polymerase chain reaction/single-strand conformation polymorphism (PCR/SSCP) and sequencing analysis to rapidly screen for mutations in p53 in colorectal...
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