Article
A role for the DP subunit of the E2F transcription factor in axis determination during Drosophila oogenesis.
Development (Cambridge, England) - 1 Aug 2000
Myster D L, Bonnette P C, Duronio R J
Abstract excerpt
The E2F family of transcription factors contributes to cell cycle control by regulating the transcription of DNA replication factors. Functional 'E2F' is a DNA-binding heterodimer composed of E2F and DP proteins. Drosophila contains two E2F genes (dE2F, dE2F2) and one DP gene (dDP). Mutation of either dE2F or dDP eliminates G(1)-S transcription of known replication factors during embryogenesis and compromises DNA...
Topics
- Animals
- Animals, Genetically Modified
- Carrier Proteins
- Cell Cycle
- Cell Cycle Proteins
- Cell Polarity
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- E2F Transcription Factors
- Female
- Genetic Complementation Test
- Germ-Line Mutation
- Insect Proteins