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Article

The Drosophila protein Dof is specifically required for FGF signaling.

Molecular cell - 1 Oct 1998

Vincent S, Wilson R, Coelho C, Affolter M, Leptin M

Abstract excerpt

Receptor tyrosine kinases (RTKs) transmit signals to the cell nucleus via the MAP kinase (MAPK) cascade, using specific molecules to link the activated receptors to the MAPK cascade activator, Ras. We have identified a component of the FGF receptor (FGFR) signal transduction pathway, Downstream of FGFR (Dof). Dof is an intracellular protein that is essential for signal transmission by the FGFR and acts downstream...

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PMID: 9809073
DOI: 10.1016/s1097-2765(00)80151-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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