Article
The use of human monocytoid lines as indicators of endotoxin.
Journal of immunological methods - 14 Aug 1996
Eperon S, Jungi T W
Abstract excerpt
We wish to develop an in vitro test system for pyrogenic substances. A major source of pyrogen activity is endotoxin. Here we describe a highly sensitive endotoxin-monitoring system based on cytokine measurement in human cell lines of myelomonocytoid origin. The following measures were taken to develop an endotoxin monitoring system of high sensitivity. (i) Mono Mac 6 (MM6) and THP-1 cells, which both represent...
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