Article
Serotonin 6 receptor polymorphism in schizophrenia: frequency, age at onset and cognitive function.
Neuropsychobiology - 1 Jan 2001
Chiu H J, Wang Y C, Liou J H, Chao C H, Lee H, Tsai K Y, Liu W C
Abstract excerpt
The relative abundance of serotonin 6 receptor (5HT6) in some limbic regions and the high affinity of some antipsychotics for 5HT6 suggest that the 5HT6 gene might play a role in the pathogenesis of schizophrenic disorders. A recent study reported an association between a C267T polymorphism of the 5HT6 gene and schizophrenia. In order to test whether the 5HT6 gene plays a role in the pathogenesis of schizophrenic...
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