Article
Association study of the 5-HT6 receptor gene in schizophrenia.
American journal of medical genetics - 16 Apr 1999
Shinkai T, Ohmori O, Kojima H, Terao T, Suzuki T, Abe K
Abstract excerpt
Serotonergic (5-hydroxytryptamine; 5-HT) transmission may play an important role in the treatment and/or pathogenesis of schizophrenia. Previous studies reported that several atypical antipsychotic agents have high affinities for the 5-HT6 receptor. The 5-HT6 receptor gene polymorphism might contribute to the genetic background of this disorder. One hundred and fifty unrelated patients with schizophrenia and 150...
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