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Article

Serotonin 6 receptor gene is associated with methamphetamine-induced psychosis in a Japanese population.

Drug and alcohol dependence - 1 Jan 2011

Kishi Taro, Fukuo Yasuhisa, Okochi Tomo, Kitajima Tsuyoshi, Kawashima Kunihiro, Naitoh Hiroshi, Ujike Hiroshi, Inada Toshiya, Yamada Mitsuhiko, Uchimura Naohisa, Sora Ichiro, Iyo Masaomi, Ozaki Norio, Iwata Nakao

Abstract excerpt

BACKGROUND: Altered serotonergic neural transmission is hypothesized to be a susceptibility factor for psychotic disorders such as schizophrenia. The serotonin 6 (5-HT6) receptor is therapeutically targeted by several second generation antipsychotics, such as clozapine and olanzapine, and d-amphetamine-induced hyperactivity in rats is corrected with the use of a selective 5-HT6 receptor antagonist. In addition,...

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Source

Identifiers

PMID: 20705401
DOI: 10.1016/j.drugalcdep.2010.06.021

Genes

HTR6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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