Article
Association analysis of the 5-HT6 receptor polymorphism C267T in Alzheimer's disease.
Neuroscience letters - 3 Dec 1999
Tsai S J, Liu H C, Liu T Y, Wang Y C, Hong C J
Abstract excerpt
Serotonergic dysfunction has been implicated in the pathogenesis of Alzheimer's disease (AD). This association study explores whether the serotonin 6 receptor (5-HT6) polymorphism (C267T) is a susceptibility factor for AD. Statistical analysis showed a significant difference in the genotype and gene frequencies between the AD group and the normal controls (P = 0.006; and P = 0.023, respectively). These findings...
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