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Article

Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism in schizophrenia is associated with age at onset and symptoms.

Neuroscience letters - 19 Jun 2006

Numata Shusuke, Ueno Shu-Ichi, Iga Jun-Ichi, Yamauchi Ken, Hongwei Song, Ohta Koji, Kinouchi Sawako, Shibuya-Tayoshi Sumiko, Tayoshi Shin'ya, Aono Michitaka, Kameoka Naomi, Sumitani Satsuki, Tomotake Masahito, Kaneda Yasuhiro, Taniguchi Takahide, Ishimoto Yasuhito, Ohmori Tetsuro

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) is a neurotrophic factor that promotes several functions of neurons and modulates neurotransmissions. It has been reported that there are alterations of BDNF levels in schizophrenic brains and that BDNF gene expressional changes would be responsible for the etiology of schizophrenia. Recent studies have shown that a variation of BDNF gene (Val66Met polymorphism) affects...

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Identifiers

PMID: 16533563
DOI: 10.1016/j.neulet.2006.02.054

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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