Article
Homogeneous assays for single-nucleotide polymorphism typing using AlphaScreen.
Genome research - 1 Apr 2001
Beaudet L, Bédard J, Breton B, Mercuri R J, Budarf M L
Abstract excerpt
AlphaScreen technology allows the development of high-throughput homogeneous proximity assays. In these assays, signal is generated when 680 nm laser light irradiates a donor bead in close proximity to an acceptor bead. For the detection of nucleic acids, donor and acceptor beads are brought into proximity by two bridging probes that hybridize simultaneously to a common target and to the generic oligonucleotides...
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