Article
Single-nucleotide polymorphism genotyping using microarrays.
Current protocols in human genetics - 1 May 2001
Patil N, Nouri N, McAllister L, Matsukaki H, Ryder T
Abstract excerpt
This unit provides a set of protocols for high throughput SNP genotyping using oligonucleotide microarrays. The basic protocol utilizes allele-specific hybridization in which the microarray provides both the allele discrimination and read-out. In the alternate approach, the allele discrimination is accomplished in solution and then the array is used to provide the read-out of the genotyping reaction. Single...
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