Article
Miniaturized sealed-tube allele-specific PCR.
Human mutation - 1 May 2002
Hawkins J Ross, Khripin Yuri, Valdes Ana M, Weaver Thomas A
Abstract excerpt
DNA diagnostics has been progressively moving from expensive, low-throughput, multi-step methods towards inexpensive, robust, and high-throughput methods. Here we describe the further validation and refinement of a recently described novel genotyping method that has the latter characteristics. An evolved form of allele-specific PCR, the method generates a fluorescent signal through the use of universal labeled...
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