Article
High-throughput genotyping assay approaches.
Pharmacogenomics - 1 Feb 2000
Kwok P Y
Abstract excerpt
High-throughput genotyping approaches are being developed to meet the demands of pharmacogenomnics, where numerous individuals are studied with thousands of single nucleotide polymorphism (SNP) markers. All non-gel-based genotyping approaches achieve allelic discrimination by one of four mechanisms: allele-specific hybridisation, allele-specific primer extension, allele-specific oligonucleotide ligation and...
Topics
- DNA Primers
- Genetic Techniques
- Genotype
- Humans
- Nucleic Acid Hybridization
- Pharmacogenetics
- Polymorphism, Single Nucleotide