Article
High-throughput genotyping of single nucleotide polymorphisms with high sensitivity.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2007
Li Honghua, Wang Hui-Yun, Cui Xiangfeng, Luo Minjie, Hu Guohong, Greenawalt Danielle M, Tereshchenko Irina V, Li James Y, Chu Yi, Gao Richeng
Abstract excerpt
The ability to analyze a large number of genetic markers consisting of single nucleotide polymorphisms (SNPs) may bring about significant advance in understanding human biology. Recent development of several high-throughput genotyping approaches has significantly facilitated large-scale SNP analysis. However, because of their relatively low sensitivity, application of these approaches, especially in studies...
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