Article
Polymorphism in promoter region of Fcalpha receptor gene in patients with IgA nephropathy.
Human genetics - 1 Feb 2001
Tsuge T, Shimokawa T, Horikoshi S, Tomino Y, Ra C
Abstract excerpt
We have recently identified two novel polymorphisms (-114T/C and +56T/C relative to the major transcription start site) in the functional promoter region of the Fcalpha receptor (FcalphaR) gene. Since altered FcalphaR expression may be associated with IgA nephropathy, we examined these promoter polymorphisms in this disease. Patients with IgA nephropathy (n = 90), patients with other primary glomerulonephritis (n...
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