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Article

Association of a T-cell receptor constant alpha chain gene polymorphism with progression of IgA nephropathy in Japanese patients.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Aug 1999

Deenitchina S S, Shinozaki M, Hirano T, Ando T, Hirakata H, Kiyohara Y, Katafuchi R, Fujishima M

Abstract excerpt

Immunogenetic studies have suggested the role of the T-cell receptor (TCR) in the development of immune-mediated diseases. We investigated whether a genetic polymorphism in the TCR constant alpha (Calpha) chain region might modify the susceptibility or progression of immunoglobulin A (IgA) nephropathy. The TCR Calpha chain genotype was studied in 213 Japanese patients with IgA nephropathy and 73 individuals from...

Read the complete abstract on PubMed

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Share to Disease Progression
Share to Glomerulonephritis, IGA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kidney Failure, Chronic

Share to Polymorphism, Restriction Fragment Length

Share to Prognosis

Share to Receptors, Antigen, T-Cell, alpha-beta

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 10430975
DOI: 10.1016/s0272-6386(99)70356-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Association of a T-cell receptor constant alpha chain gene polymorphism with progression of IgA nephropathy in Japanese patients.PMID 10430975Read ↗

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