Article
Polymorphism of renin-angiotensin system genes in IgA nephropathy.
Nephrology (Carlton, Vic.) - 1 Oct 2004
Woo Keng-Thye, Lau Yeow-Kok, Choong Lina Hl, Zhao Yi, Tan Hwee-Boon, Fook-Chong Stephanie, Tan Eng-King, Yap Hui-Kim, Wong Kok-Seng
Abstract excerpt
BACKGROUND AND AIMS: Individuals are prone to disease because of certain disease-susceptible genes. The angiotensin I-converting enzyme (ACE) gene insertion/deletion (I/D), the angiotensinogen (AGT) gene, M235T, and the angiotensin II type 1 receptor (ATR) gene, A1166C, polymorphisms have been associated with IgA nephropathy (IgAN) and its progression. Several studies on Caucasians and Japanese patients have...
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