Article
Association of -27T>C and its haplotype at the putative promoter for IgA-specific receptor gene with IgA nephropathy among the Chinese Han population.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Aug 2011
Huang Weijun, Gu Hongbiao, Li Ru, Lou Tanqi, Zhang Jun, Shi Wei, Ye Zhiming, Zhou Yan, Li Caixia, Xiong Shiyi, Li Li, Wu Changyou, Leung Joseph C K, Lam Man F, Lai Kar N, Wang Yiming
Abstract excerpt
BACKGROUND: One-third to half of IgA nephropathy (IgAN) patients have raised serum IgA levels. Decreased clearance of IgA/IgA complex has been observed in IgAN patients. FCAR codes for IgA-specific receptor and plays an important role in IgA metabolism. Previous small sample-sized studies reporte...
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