Article
Genetic variants of the IgA Fc receptor (FcalphaR, CD89) promoter in chronic hepatitis C patients.
Immunogenetics - 1 Dec 2006
Watanabe Azuma, Shimokawa Toshibumi, Moriyama Mitsuhiko, Komine Fumihiko, Amaki Shuichi, Arakawa Yasuyuki, Ra Chisei
Abstract excerpt
Fc receptor for IgA (FcalphaR, CD89) is capable of triggering IgA-mediated immune responses to pathogens and has been proposed to function in circulating IgA clearance. Because inheritable variations modifying individual immune responses or immunoglobulin catabolism may affect the chronicity of viral infection, we investigated whether promoter polymorphisms of the FcalphaR gene (FCAR) affect chronic hepatitis C...
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