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Article

Mitochondrial DNA mutations in disease and ageing.

Novartis Foundation symposium - 1 Jan 2001

Cottrell D A, Blakely E L, Johnson M A, Borthwick G M, Ince P I, Turnbull D M

Abstract excerpt

The chronological accumulation of mitochondrial DNA mutations has been proposed as a potential mechanism in the physiological processes of ageing and age-related disease. We discuss the evidence behind this theory and relate some of the ageing mitochondrial changes to mitochondrial DNA disorders....

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PMID: 11280028
DOI: 10.1002/0470868694.ch19

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11280028-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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