Article
Mitochondrial involvement in the ageing process. Facts and controversies.
Molecular and cellular biochemistry - 1 Sept 1997
Brierley E J, Johnson M A, James O F, Turnbull D M
Abstract excerpt
Mitochondria are believed to be involved in human ageing. Whilst it is clear that various mitochondrial DNA mutations do accumulate in human tissues with age, whether or not they interfere with respiratory chain function is uncertain. We question the results of previous studies which have measured respiratory chain function in human skeletal muscle with age. Whilst cytochrome c oxidase deficient fibres are a real...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.