Carcinogenesis: mutations and mutagens.

Abstract excerpt

In normal human cells there is a steady accumulation of mutations with time. We argue that the great majority of these mutations arise spontaneously and are due to endogenous factors or processes that damage DNA. A small fraction of these mutations converts a normal cell into a cell that is initiated towards the development of cancer. We propose that, in general, these initiated cells are more susceptible to the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Age Factors
• Share to Mutagens
• Share to Mutation