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Article

Inhibition of p53-dependent transcription by BOX-I phospho-peptide mimetics that bind to p300.

EMBO reports - 1 Feb 2001

Dornan D, Hupp T R

Abstract excerpt

The N-terminal BOX-I domain of p53 containing a docking site for the negative regulator MDM2 and the positive effector p300, harbours two recently identified phosphorylation sites at Thr18 or Ser20O whose affect on p300 is undefined. Biochemical assays demonstrate that although MDM2 binding is in...

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Identifiers

PMID: 11258706
DOI: 10.1093/embo-reports/kve025
PMCID: PMC1083821

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11258706-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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