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Article

JMJD3 is a histone H3K27 demethylase.

Cell research - 1 Oct 2007

Xiang Yang, Zhu Ziqi, Han Gang, Lin Hanqing, Xu Longyong, Chen Charlie Degui

Abstract excerpt

Histone methylation is an important epigenetic phenomenon that participates in a diverse array of cellular processes and has been found to be associated with cancer. Recent identification of several histone demethylases has proved that histone methylation is a reversible process. Through a candidate approach, we have biochemically identified JMJD3 as an H3K27 demethylase. Transfection of JMJD3 into HeLa cells...

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Identifiers

PMID: 17923864
DOI: 10.1038/cr.2007.83

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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