Article
Defective initiation in an Escherichia coli dnaA(Cs,Sx) mutant.
Biochimie - 1 Jan 2001
Boye E, Blinkova A, Walker J R
Abstract excerpt
Mutations in the Escherichia coli gene for initiation of DNA replication, dnaA, which suppress the polymerization defect and growth inhibition caused by temperature-sensitive (Ts) mutations in the polymerization gene, dnaX, are called Cs,Sx. We show here that these mutations, on their own, also cause defects in initiation, including inhibition of initiation at both low (20 degrees C) and high (44 degrees C)...
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