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Article

Initiation of chromosomal DNA replication which is stimulated without oversupply of DnaA protein in Escherichia coli.

Molecular & general genetics : MGG - 1 May 1991

Katayama T, Nagata T

Abstract excerpt

The temperature-sensitive dnaA46 mutation in Escherichia coli can be phenotypically suppressed at 42 degrees C by oversupply of GroELS proteins, and the suppressed cells grow extremely slowly at 30 degrees C. We found that the phenotype of dnaA46 showing this cold sensitivity was dominant over the phenotype of dnaA+, and could not be rescued by introduction of oriC-independent replication systems. These results...

Topics

Bacterial Proteins
Bacteriophage lambda
Blotting, Western
Chromosomes, Bacterial
DNA Replication
DNA-Binding Proteins
Escherichia coli
Genes, Bacterial
Genes, Viral
Nucleic Acid Hybridization
Phenotype

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Identifiers

PMID: 1828106
DOI: 10.1007/BF00260663

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1828106-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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