Article
No evidence of association from transmission disequilibrium analysis of the hKCa3 gene in bipolar disorder.
Bipolar disorders - 1 Dec 2000
Bowen T, Ashworth L, Kirov G, Guy C A, Jones I R, McCandless F, Craddock N, O'Donovan M C, Owen M J
Abstract excerpt
OBJECTIVE: A recent case control study has suggested that modest enlargements of a highly polymorphic CAG repeat in exon 1 of the gene encoding potassium channel hKCa3 may be associated with bipolar disorder (BPD). We have examined this hypothesis by genotyping this locus in a family-based association study. METHOD: One hundred and twenty-eight parent offspring trios of British Caucasian origin were examined...
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