Article
No association between a polymorphic CAG repeat in the human potassium channel gene hKCa3 and bipolar disorder.
American journal of medical genetics - 5 Feb 1999
Guy C A, Bowen T, Williams N, Jones I R, McCandless F, McGuffin P, Owen M J, Craddock N, O'Donovan M C
Abstract excerpt
A recent case-control study suggested that modest enlargements of a CAG repeat in the hKCa3 potassium channel may be associated with bipolar disorder. We tried to replicate this result in a UK Caucasian sample of 203 DSM-IV bipolar I disorder patients and 206 controls group-matched for age and sex. Using the same model of analysis as the earlier study, bipolar probands did not have a higher frequency of alleles...
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