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Article

hSKCa3: a candidate gene for schizophrenia?

Psychiatric genetics - 1 Jun 1999

Meissner B, Purmann S, Schürmann M, Zühlke C, Lencer R, Arolt V, Müller-Myhsok B, Morris-Rosendahl D J, Schwinger E

Abstract excerpt

Recently, case-control studies have suggested an association between the polymorphic CAG repeat in the neuronal potassium channel gene hSKCa3 and an increased susceptibility to schizophrenia, with larger repeats being overrepresented in schizophrenic patients. Therefore, we have examined the CAG repeat polymorphism in hSKCa3 and four adjacent microsatellite markers in 12 multiplex schizophrenia families. On...

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PMID: 10412188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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Related research

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Research trail→

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hSKCa3: a candidate gene for schizophrenia?PMID 10412188Read ↗

Short CAG repeats within the hSKCa3 gene associated with schizophrenia: results of a family-based study.Semantic proximity Read ↗

Isolation of a novel potassium channel gene hSKCa3 containing a polymorphic CAG repeat: a candidate for schizophrenia and bipolar disorder?Semantic proximity Read ↗

Lack of linkage or association between schizophrenia and the polymorphic trinucleotide repeat within the KCNN3 gene on chromosome 1q21.Semantic proximity Read ↗

Lack of association between the hSKCa3 channel gene CAG polymorphism and schizophrenia.Semantic proximity Read ↗

Association between hSKCa3 and schizophrenia not confirmed by transmission disequilibrium test in 193 offspring/parents trios.Semantic proximity Read ↗

No evidence to support the association of the potassium channel gene hSKCa3 CAG repeat with schizophrenia or bipolar disorder in the Irish population.Semantic proximity Read ↗

The human small conductance calcium-regulated potassium channel gene (hSKCa3) contains two CAG repeats in exon 1, is on chromosome 1q21.3, and shows a possible association with schizophrenia.Semantic proximity Read ↗

hKCNN3 which maps to chromosome 1q21 is not the causative gene in periodic catatonia, a familial subtype of schizophrenia.Semantic proximity Read ↗

Mapping of hKCa3 to chromosome 1q21 and investigation of linkage of CAG repeat polymorphism to schizophrenia.Semantic proximity Read ↗

Further support for an association between a polymorphic CAG repeat in the hKCa3 gene and schizophrenia.Semantic proximity Read ↗

Genetic association study of a polymorphic CAG repeats array of calcium-activated potassium channel (KCNN3) gene and schizophrenia among the Chinese population from Taiwan.Semantic proximity Read ↗

CAG-repeat length in exon 1 of KCNN3 does not influence risk for schizophrenia or bipolar disorder: a meta-analysis of association studies.Semantic proximity Read ↗

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