Article
Short CAG repeats within the hSKCa3 gene associated with schizophrenia: results of a family-based study.
Neuroreport - 16 Nov 1998
Stöber G, Jatzke S, Meyer J, Okladnova O, Knapp M, Beckmann H, Lesch K P
Abstract excerpt
In a family-based association study we investigated transmission of a multiallelic CAG repeat in a novel neuronal potassium channel gene, hSKCa3, in 59 parent/ offspring trios. In contrast to recent reports of an association of moderately large repeats with schizophrenia in case-control studies,...
Topics
- Adolescent
- Adult
- Alleles
- DNA Mutational Analysis
- Family Health
- Female
- Genetic Linkage
- Genotype
- Humans
- Male
- Neuropeptides
- Pedigree
- Polymorphism, Genetic
- Potassium Channels
- Schizophrenia
- Small-Conductance Calcium-Activated Potassium Channels
- Trinucleotide Repeats