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Article

Analysis of ANK3 and CACNA1C variants identified in bipolar disorder whole genome sequence data.

Bipolar disorders - 1 Sept 2014

Fiorentino Alessia, O'Brien Niamh Louise, Locke Devin Paul, McQuillin Andrew, Jarram Alexandra, Anjorin Adebayo, Kandaswamy Radhika, Curtis David, Blizard Robert Alan, Gurling Hugh Malcolm Douglas

Abstract excerpt

OBJECTIVES: Genetic markers in the genes encoding ankyrin 3 (ANK3) and the α-calcium channel subunit (CACNA1C) are associated with bipolar disorder (BP). The associated variants in the CACNA1C gene are mainly within intron 3 of the gene. ANK3 BP-associated variants are in two distinct clusters at the ends of the gene, indicating disease allele heterogeneity. METHODS: In order to screen both coding and non-coding...

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Identifiers

PMID: 24716743
DOI: 10.1111/bdi.12203
PMCID: PMC4227602

Genes

ANK3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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