Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic alterations and expression of the protein phosphatase 1 genes in human cancers.

International journal of oncology - 1 Apr 2001

Takakura S, Kohno T, Manda R, Okamoto A, Tanaka T, Yokota J

Abstract excerpt

Recent studies have revealed that genetic alterations of the protein phosphatase genes, including PTEN, PPP2R1A, PPP2R1B and PPP1R3, are involved in human carcinogenesis. In the present study, we examined the genetic and expression status of nine protein phosphatase 1 (PP1) genes in 55 human cancer cell lines, consisting of 10 small cell lung cancers, 22 non-small cell lung cancers, 11 colorectal cancers, 7...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Primers
Share to Genes, Tumor Suppressor
Share to Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phosphoprotein Phosphatases

Share to Phosphoric Monoester Hydrolases

Share to Protein Phosphatase 1

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 11251179
DOI: 10.3892/ijo.18.4.817

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic alterations and expression of the protein phosphatase 1 genes in human cancers.PMID 11251179Read ↗

Alterations of the PPP1R3 gene in human cancer.Semantic proximity Read ↗

Low frequency of alterations of the alpha (PPP2R1A) and beta (PPP2R1B) isoforms of the subunit A of the serine-threonine phosphatase 2A in human neoplasms.Semantic proximity Read ↗

Somatic mutations and genetic polymorphisms of the PPP1R3 gene in patients with several types of cancers.Semantic proximity Read ↗

Infrequent mutations of the PPP2R1A and PPP2R1B genes in patients with ovarian cancer.Semantic proximity Read ↗

Functional genetic polymorphisms in PP2A subunit genes confer increased risks of lung cancer in southern and eastern Chinese.Semantic proximity Read ↗

Somatic mutations of PPP2R1A in ovarian and uterine carcinomas.Semantic proximity Read ↗

PPP2R1A mutation is a rare event in ovarian carcinoma across histological subtypes.Semantic proximity Read ↗

Protein phosphatase 1 in tumorigenesis: is it worth a closer look?Semantic proximity Read ↗

The role of phosphoprotein phosphatases catalytic subunit genes in pancreatic cancerSemantic proximity Read ↗

A brief introduction to the protein phosphatase families.Semantic proximity Read ↗

Genetic variants in PPP2CA are associated with gastric cancer risk in a Chinese population.Semantic proximity Read ↗

Genetic alterations of protein tyrosine phosphatases in human cancers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.