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Article

Infrequent mutations of the PPP2R1A and PPP2R1B genes in patients with ovarian cancer.

Molecular medicine reports - 1 Jun 2013

Wang Feng, Zou Yang, Liu Fa-Ying, Yu Xiao-Hong, Huang Huang, Zhang Nan, Qi Ying-Ying, Liu Rong-Fang, Liu Xiao-Yan, Chen Jia, Huang Ou-Ping, He Ming

Abstract excerpt

Protein phosphatase 2, regulatory subunit A, α (PPP2R1A) and β (PPP2R1B) are paralogous subunits of the heterotrimeric protein phosphatase 2 (PP2A) holoenzyme that catalyzes the dephosphorylation of target substrate proteins. Subtype‑specific PPP2R1A mutations have been frequently observed in ovarian and endometrial cancer. Mutations in the paralogous genes were frequently observed in human malignancies. Thus,...

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PMID: 23588898
DOI: 10.3892/mmr.2013.1416

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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