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Genetic variants in PPP2CA are associated with gastric cancer risk in a Chinese population.

Scientific reports - 13 Sept 2017

Huang Tongtong, He Kexin, Mao Yingying, Zhu Meng, Yan Caiwang, Yu Fei, Qi Qi, Wang Tianpei, Wang Yan, Du Jiangbo, Liu Li

Abstract excerpt

Protein phosphatase 2A (PP2A), a tumor suppressor protein, has been implicated in cell cycle and apoptosis. Additionally, studies have illustrated its crucial roles in transformation of normal human cells to tumorigenic status. PPP2CA, which encodes the alpha isoform of the catalytic subunit of PP2A, has been recently reported to be associated with several types of cancers. Therefore, we hypothesized that genetic...

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Identifiers

PMID: 28904398
DOI: 10.1038/s41598-017-12040-z
PMCID: PMC5597632

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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