Article
Mutations in the coding region of the neurogenin 3 gene (NEUROG3) are not a common cause of maturity-onset diabetes of the young in Japanese subjects.
Diabetes - 1 Mar 2001
del Bosque-Plata L, Lin J, Horikawa Y, Schwarz P E, Cox N J, Iwasaki N, Ogata M, Iwamoto Y, German M S, Bell G I
Abstract excerpt
Mutations in transcription factors that play a role in the development of the endocrine pancreas, such as insulin promoter factor-1 and NeuroD1/BETA2, have been associated with diabetes. Cell type-specific members of the basic helix-loop-helix (bHLH) family of transcription factors play essential roles in the development and maintenance of many differentiated cell types, including pancreatic beta-cells....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.