Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3.

Molecular and cellular biology - 1 May 2000

Huang H P, Liu M, El-Hodiri H M, Chu K, Jamrich M, Tsai M J

Abstract excerpt

The BETA2 (neuroD) gene is expressed in endocrine cells during pancreas development and is essential for proper islet morphogenesis. The objective of this study is to identify potential upstream regulators of the BETA2 gene during pancreas development. We demonstrated that the expression of neurogenin 3 (ngn3), an islet- and neuron-specific basic-helix-loop-helix transcription factor, partially overlaps that of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Xenopus
Share to 3T3 Cells
Share to Basic Helix-Loop-Helix Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Blotting, Northern

Share to HeLa Cells

Share to Nerve Tissue Proteins

Share to Pancreas

Share to Up-Regulation

Source

Open in PubMed Open full text

Identifiers

PMID: 10757813
DOI: 10.1128/MCB.20.9.3292-3307.2000
PMCID: PMC85623

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3.PMID 10757813Read ↗

Neurogenin3 Activates the Islet Differentiation Program while Repressing Its Own ExpressionSemantic proximity Read ↗

Regulation of the Pancreatic Pro-Endocrine Gene <i>Neurogenin3</i>Semantic proximity Read ↗

Neurogenin3 Cooperates with Foxa2 to Autoactivate Its Own ExpressionSemantic proximity Read ↗

Expression of Insulinoma-Associated 2 (INSM2) in Pancreatic Islet Cells Is Regulated by the Transcription Factors Ngn3 and NeuroD1Semantic proximity Read ↗

Defining Pancreatic Endocrine Precursors and Their DescendantsSemantic proximity Read ↗

NeuroD: the predicted and the surprising.Semantic proximity Read ↗

Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3.Semantic proximity Read ↗

The expression order determines the pioneer functions of NGN3 and NEUROD1 in pancreatic endocrine differentiationSemantic proximity Read ↗

The Basic Helix-Loop-Helix Transcription Factor NEUROG3 Is Required for Development of the Human Endocrine Pancreas.Semantic proximity Read ↗

PDX1, Neurogenin-3, and MAFA: critical transcription regulators for beta cell development and regenerationSemantic proximity Read ↗

Distinct Gene Expression Programs Function in Progenitor and Mature Islet CellsSemantic proximity Read ↗

NEUROD1 Is Required for the Early α and β Endocrine Differentiation in the PancreasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.