Article
Variants of neurogenin 3 gene are not associated with Type II diabetes in Japanese subjects.
Diabetologia - 1 Feb 2001
Okada T, Tobe K, Hara K, Yasuda K, Kawaguchi Y, Ikegami H, Ito C, Kadowaki T
Abstract excerpt
AIMS/HYPOTHESIS: Neurogenin 3 (ngn3) is a transcription factor expressed in the endocrine precursor cells of the pancreas. It has recently been reported that ngn3-deficient mice show absence of pancreatic endocrine cells and die of postnatal diabetes. The purpose of this investigation was to scre...
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