Article
Mutation screening of the neurogenin-3 gene in autosomal dominant diabetes.
The Journal of clinical endocrinology and metabolism - 1 May 2001
Kim S H, Warram J H, Krolewski A S, Doria A
Abstract excerpt
We investigated whether genetic variability in neurogenin-3, a basic helix-loop-helix transcription factor that is expressed in the developing pancreas, contributes to the etiology of maturity-onset diabetes of the young or other forms of autosomal dominant diabetes. Ninety-one probands of families with autosomal dominant diabetes were screened for neurogenin-3 mutations by dideoxy fingerprinting. Three sequence...
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