Article
A genome-wide search for genes involved in type 2 diabetes in a recently genetically isolated population from the Netherlands.
Diabetes - 1 Dec 2003
Aulchenko Yurii S, Vaessen Norbert, Heutink Peter, Pullen Jan, Snijders Pieter J L M, Hofman Albert, Sandkuijl Lodewijk A, Houwing-Duistermaat Jeanine J, Edwards Mark, Bennett Simon, Oostra Ben A, van Duijn Cornelia M
Abstract excerpt
Multiple genes, interacting with the environment, contribute to the susceptibility to type 2 diabetes. We performed a genome-wide search to localize type 2 diabetes susceptibility genes in a recently genetically isolated population in the Netherlands. We identified 79 nuclear families with type 2 diabetes who were related within 13 generations and performed a 770-marker genome-wide scan search for shared founder...
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