Article
A locus affecting obesity in human chromosome region 10p12.
Diabetologia - 1 Mar 2001
Price R A, Li W D, Bernstein A, Crystal A, Golding E M, Weisberg S J, Zuckerman W A
Abstract excerpt
AIMS/HYPOTHESIS: Obesity is a complex trait influenced by multiple genes. We evaluated linkage in three regions of human chromosome 10 previously linked to obesity-related phenotypes. METHODS: We conducted non-parametric linkage analysis of obesity-related phenotypes in cohorts of 170 European-American and 43 African-American families having extremely obese and normal weight subjects. RESULTS: We found support...
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