Article
Hardy-Weinberg quality control.
Annals of human genetics - 1 Nov 1999
Gomes I, Collins A, Lonjou C, Thomas N S, Wilkinson J, Watson M, Morton N
Abstract excerpt
An efficient test of deviation from Hardy-Weinberg frequencies with one degree of freedom was applied to 44 marker loci in a genome scan, and 7 loci had a significant excess of apparent homozygotes (chi2 (1) > 6) suggestive of typing error. In this example evidence for linkage did not increase wh...
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