Article
Hardy-Weinberg Equilibrium in Meta-Analysis Studies and Large-Scale Genomic Sequencing Era.
Asian Pacific journal of cancer prevention : APJCP - 1 Jul 2024
Neamatzadeh Hossein, Dastgheib Seyed Alireza, Mazaheri Mahta, Masoudi Ali, Shiri Amirmasoud, Omidi Amirhossein, Rahmani Amirhossein, Golshan-Tafti Ahmadreza, Aghasipour Maryam, Yeganegi Maryam, Bahrami Mohammad, Aghili Kazem, Khajehnoori Sahel, Mosavi Jarrahi Alireza
Abstract excerpt
The Hardy-Weinberg Equilibrium (HWE) is a fundamental principle employed in the analysis of genetic data, encompassing studies of meta-analysis and genomic sequencing. It has been demonstrated that HWE possesses the property of transitivity, wherein a multi-allelic polymorphism in equilibrium will persist in its equilibrium state even when alleles are deleted or combined. Nonetheless, the practice of filtering...
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